Platform
ARTUN™
The initial hype around the use of Artificial Intelligence (AI) to understand disease and develop better medicines now seems to be making ways to important achievements.
Nutrasilic has deployed an AI-powered platform (ARTUN™) and is taking advantage of bioinformatics, cheminformatics and AI to unlock novel health benefits of natural ingredients – be they food nutrients, phytochemicals or natural substances from marine origin.
Process
mapping the Human-Nature interactome
1. In Silico Mapping of NTIs
Prediction of natural compound-target interactions (NTIs) and synergy in multi-molecular properties employing cheminformatics, systems biology, and AI-based approaches.
2. Molecular Repurposing
Critical assessment of multi-component target networks and ranking of hypothetical links employing structural bioinformatics – definition of unique value proposition
3. Experimental Validation
Confirmation of target and/or mechanism hypothesis employing proteomics, in vitro and in-cell (phenotypic) studies
4. Development of Nutraceutical or Natural Product
Establishment of an evidence-based target-product profile (TPP) to be prototyped/formulated as a value-added and credible healthcare product
Areas of activity
focusing on well-being, delivering unprecedented health benefits
Nutrasilic is building a portfolio of nature-derived products for a wide range of industrial partners who wish to enrich their portfolio with science-backed natural products with proven health benefits.
Homeostasis & healthy aging
Homeostasis is a complex self-regulating process that maintains the physiological balance of living systems. The human body’s ability to correct temporary imbalances and re-establish its optimal equilibrium can be boosted by natural substances.
Nutrasilic is testing new and natural ways of modulating key proteins that play a role in regulating the body’s natural clearance and defence mechanisms throughout aging. We are also targeting enzymes that regulate the body’s energy requirements, as well as the storage, release, and tissue delivery of nutrients.
Gut health
Mounting scientific evidence is shading light over the role of gut microbiota in a healthy development and prevention of gut inflammation and disease.
Nutrasilic is using their AI-powered platform and virtual library of natural substances to probe and modulate microbiota-gut-brain links associated with obesity, inflammatory bowel disorder and chronic constipation.
Pain relief
Chronic pain associated with several conditions is an increasing concern in modern societies, still anchored into synthetic solutions.
Nutrasilic explores molecular targets aiming to discover natural solutions to enhance response to pain and inflammation.
Skin care
Even though synthetic ingredients still dominate the skin care market, demand for natural anti-aging, antioxidants, or skin whitening cosmetics is growing along with the consumer preference for organic and natural products that contain minimal additives and may have fewer side effects.
Nutrasilic has taken efforts to map novel molecular targets of relevance to skin health and aging, and is screening its library for natural compounds for interference with such targets.
Treatment enhancement
Drug interactions with food ingredients often affect treatment outcomes – either positively or negatively – and may cause adverse effects.
Nutrasilic is seeking to take advantage of drug-food synergies to fine-tune drug effects, including the modulation of the action of prodrugs and soft drugs in specific patient populations. The multifactorial nature of many conditions prompts us to embrace a holistic approach and devise patient-centered strategies.
Mission & Values
nutraceutical innovation through sustainable scientific approaches
Nutrasilic’s mission is to help people achieve and maintain their wellbeing through nutraceuticals and natural products crafted with resource to rational and Science-backed in silico methods.
Our vision is to become, within the next 10 years, a global reference and trusted partner in the development of innovative healthcare products.
About us
Nutrasilic emerges from a motivation to develop Science-based and credible nutraceuticals
Nutrasilic sprouts from the motivation of five friends, colleagues, but mostly entrepreneurs coming from different settings of the biotech and pharmaceutical sectors, willing to combine their competences, skills and know-how to bring novelty into the Healthcare product market.
We aim for innovation in the development of nutraceuticals and natural products, including dietary supplements and cosmetics, by applying in silico technologies in combination with scientific practices and validation.
Currently, the company is validating a first set of target-compound links unraveled in silico, having already experimentally confirmed potent engagement with several targets of pharmaceutical relevance. At the same time, the company is ensuring the protection of the intellectual assets already generated and probing the commercial interest of industrial partners.
Contact
embracing open and joint innovation
Partnerships – Seeking Collaborations
Nutrasilic is open (and actively seeking) to partnering with leading food and pharmaceutical corporations to fulfil its vision of revolutionizing the use of Nature’s chemical toolbox to deliver true Science-based health benefits.
Contact us at info[at]nutrasilic.com
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